质粒类型：慢毒载体

载体大小：7861 bp

克隆方法：多克隆位点，限制性内切酶

载体抗性：Ampicillin (氨苄青霉素)

筛选标记：Puromycin

miRZip anti-sense microRNAs are stably expressed RNAi hairpins that produce mature anti-microRNAs. These miRZips antagonize its endogenous microRNA target and inhibit its function.

The miRZip construct produces high levels of anti-sense small RNAs that target a specific microRNA. Upon binding, the miRZip provides a more stable template for the microRNA to bind to and sequestering it from participating in RISC-associated target mRNA translation inhibition.

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