HG-HO002827
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HG-HO002827

产品货号：HG-HO002827
产品类型：ORF表达质粒
装载载体：pMD19-T Simple Vector
基因信息：Homo sapiens protein tyrosine phosphatase non-receptor type 1 (PTPN1，PTP1B), transcript variant 1, mRNA
出货周期：现货
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产品概述
产品说明书
质粒图谱
基因简介
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产品概述
产品名称HG-HO002827产品类型ORF表达质粒
产品货号HG-HO002827装载载体pMD19-T Simple Vector
基因信息Homo sapiens protein tyrosine phosphatase non-receptor type 1 (PTPN1，PTP1B), transcript variant 1, mRNA NCBI序列号NM_002827
出货周期现货
产品说明书

TS-PTPN1（HG-HO002827）产品说明书.pdf

质粒图谱

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基因简介

PTP1B, also known as PTPN1, belongs to the protein-tyrosine phosphatase (PTP) family. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTP1B contains 1 tyrosine-protein phosphatase domain and is expressed in many tissues. PTP1B is localized to the cytoplasmic face of the endoplasmic reticulum. PTP1B was also reported to dephosphorylate epidermal growth factor receptor kinase, as well as JAK2 and TYK2 kinases, which implicated the role of PTP1B in cell growth control, and cell response to IFN stimulation.

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