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rAd-KDR

产品货号:HG-rAd002253
产品类型:Human
基因信息:Homo sapiens kinase insert domain receptor (a type III receptor tyrosine kinase)(KDR,CD309,FLK1,VEGFR,VEGFR2), mRNA
出货周期:7-8 周
产品概述
基因简介
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产品概述
产品名称rAd-KDR产品类型Human
产品货号HG-rAd002253基因信息Homo sapiens kinase insert domain receptor (a type III receptor tyrosine kinase)(KDR,CD309,FLK1,VEGFR,VEGFR2), mRNA
NCBI序列号NM_002253出货周期7-8 周
基因简介

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.