rAd-4-MDM2
产品货号：HG-rAd002392
产品类型：Human
基因信息：Homo sapiens MDM2 oncogene, E3 ubiquitin protein ligase (MDM2，ACTFS，hdm2，HDMX),transcript variant 1, mRNA
出货周期：6-7 周
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| 产品名称 | rAd-4-MDM2 | 产品类型 | Human |
| 产品货号 | HG-rAd002392 | 基因信息 | Homo sapiens MDM2 oncogene, E3 ubiquitin protein ligase (MDM2，ACTFS，hdm2，HDMX),transcript variant 1, mRNA |
| NCBI序列号 | NM_002392 | 出货周期 | 6-7 周 |
基因简介
This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells.
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