rAd-4-PTPN1
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rAd-4-PTPN1

产品货号：HG-rAd002827
产品类型：过表达腺病毒
基因信息：Homo sapiens protein tyrosine phosphatase, non-receptor type 1(PTPN1，PTP1B), transcript variant 1, mRNA
出货周期：6-7 周
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产品概述
基因简介
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产品概述
产品名称rAd-4-PTPN1产品类型过表达腺病毒
产品货号HG-rAd002827基因信息Homo sapiens protein tyrosine phosphatase, non-receptor type 1(PTPN1，PTP1B), transcript variant 1, mRNA
NCBI序列号NM_002827出货周期6-7 周
基因简介

PTP1B, also known as PTPN1, belongs to the protein-tyrosine phosphatase (PTP) family. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTP1B contains 1 tyrosine-protein phosphatase domain and is expressed in many tissues. PTP1B is localized to the cytoplasmic face of the endoplasmic reticulum. PTP1B was also reported to dephosphorylate epidermal growth factor receptor kinase, as well as JAK2 and TYK2 kinases, which implicated the role of PTP1B in cell growth control, and cell response to IFN stimulation.

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