产品概述
| 产品名称 | MO019812 | 产品类型 | ORF表达质粒 |
| 产品货号 | HG-MO019812 | 装载载体 | pcDNA3.1(+) |
| 基因信息 | (C端带3xFlag标签)Mus musculus sirtuin 1 (Sirt1), transcript variant 1, mRNA | NCBI序列号 | NM_019812 |
| 出货周期 | 现货 | ||
产品说明书
质粒图谱

基因简介
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants.
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