HG-GHO00143
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HG-GHO00143

产品货号：HG-GHO00143
产品类型：ORF表达质粒
装载载体：pcDNA3.1(+)
基因信息：（C端带3xHA标签）Homo sapiens E1A binding protein p300 (EP300, KAT3B), transcript variant 1, mRNA
出货周期：现货
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产品概述
质粒图谱
基因简介
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产品概述
产品名称HG-GHO00143产品类型ORF表达质粒
产品货号HG-GHO00143装载载体pcDNA3.1(+)
基因信息（C端带3xHA标签）Homo sapiens E1A binding protein p300 (EP300, KAT3B), transcript variant 1, mRNA NCBI序列号NM_001429
出货周期现货
质粒图谱

pcDNA3.1(+).jpg

基因简介

This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer.

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