HG-HO002336
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HG-HO002336

产品货号：HG-HO002336
产品类型：ORF表达质粒
装载载体：pcDNA3.1(+)
基因信息：（C端带3xFlag标签）Homo sapiens LDL receptor related protein 6 (LRP6), mRNA
出货周期：现货
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产品概述
质粒图谱
基因简介
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产品概述
产品名称HG-HO002336产品类型ORF表达质粒
产品货号HG-HO002336装载载体pcDNA3.1(+)
基因信息（C端带3xFlag标签）Homo sapiens LDL receptor related protein 6 (LRP6), mRNA NCBI序列号NM_002336
出货周期现货
质粒图谱

pcDNA3.1(+).jpg

基因简介

This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.

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