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HG-GHO00110

产品货号:HG-GHO00110
产品类型:ORF表达质粒
装载载体:pcDNA3.1(+)
基因信息:(N端带flag标签)Homo sapiens cortactin (CTTN), transcript variant 1, mRNA
出货周期:现货
产品概述
产品说明书
质粒图谱
基因简介
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产品概述
产品名称HG-GHO00110产品类型ORF表达质粒
产品货号HG-GHO00110装载载体pcDNA3.1(+)
基因信息(N端带flag标签)Homo sapiens cortactin (CTTN), transcript variant 1, mRNA NCBI序列号NM_005231
出货周期现货
产品说明书
质粒图谱

pcDNA3.1-Flag-CTTN.png

基因简介

This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene.