产品概述
| 产品名称 | HG-GHO00110 | 产品类型 | ORF表达质粒 |
| 产品货号 | HG-GHO00110 | 装载载体 | pcDNA3.1(+) |
| 基因信息 | (N端带flag标签)Homo sapiens cortactin (CTTN), transcript variant 1, mRNA | NCBI序列号 | NM_005231 |
| 出货周期 | 现货 | ||
产品说明书
质粒图谱

基因简介
This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene.
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