0 篇引用文献

HG-GHO00200

产品货号:HG-GHO00200
产品类型:ORF表达质粒
装载载体:pcDNA3.1(+)
基因信息:(C端带3xFlag标签)Homo sapiens kinase insert domain receptor (KDR, VEGFR2), mRNA
出货周期:现货
产品概述
产品说明书
质粒图谱
基因简介
相关产品推荐
产品概述
产品名称HG-GHO00200产品类型ORF表达质粒
产品货号HG-GHO00200装载载体pcDNA3.1(+)
基因信息(C端带3xFlag标签)Homo sapiens kinase insert domain receptor (KDR, VEGFR2), mRNA NCBI序列号NM_002253
出货周期现货
产品说明书
质粒图谱

pcDNA3.1-KDR-3xFlag.png

基因简介

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.