产品概述
| 产品名称 | HG-GHO00200 | 产品类型 | ORF表达质粒 |
| 产品货号 | HG-GHO00200 | 装载载体 | pcDNA3.1(+) |
| 基因信息 | (C端带3xFlag标签)Homo sapiens kinase insert domain receptor (KDR, VEGFR2), mRNA | NCBI序列号 | NM_002253 |
| 出货周期 | 现货 | ||
产品说明书
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基因简介
Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.
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