HG-MO007715
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HG-MO007715

产品货号：HG-MO007715
产品类型：ORF表达质粒
装载载体：pcDNA3.1-3xFlag-C
基因信息：（C端带3xFlag标签）Mus musculus clock circadian regulator (Clock), transcript variant 1, mRNA
出货周期：现货
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产品概述
产品说明书
质粒图谱
基因简介
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产品概述
产品名称HG-MO007715产品类型ORF表达质粒
产品货号HG-MO007715装载载体pcDNA3.1-3xFlag-C
基因信息（C端带3xFlag标签）Mus musculus clock circadian regulator (Clock), transcript variant 1, mRNA NCBI序列号NM_007715
出货周期现货
产品说明书

pcDNA3.1-musClock-3xFlag产品说明书.pdf

质粒图谱

pcDNA3.1-musClock-3xFlag.png

基因简介

The protein encoded by this gene plays a central role in the regulation of circadian rhythms. The protein encodes a transcription factor of the basic helix-loop-helix (bHLH) family and contains DNA binding histone acetyltransferase activity. The encoded protein forms a heterodimer with Arntl (Bmal1) that binds E-box enhancer elements upstream of Period (Per1, Per2, Per3) and Cryptochrome (Cry1, Cry2) genes and activates transcription of these genes. Per and Cry proteins heterodimerize and repress their own transcription by interacting in a feedback loop with Clock/Arntl complexes. Polymorphisms in this gene may be associated with behavioral changes, obesity, and metabolic syndrome. Two transcripts encoding the same protein have been found for this gene. [provided by RefSeq, Jan 2014]

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